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An alkaloid is a generic term to define a nitrogen-based molecule. There are many kinds such as nicotine which is a tobacco alkaloid there is also cotinine, nornicotine, anatabine, anabasine, nicotine N oxide, myosmine and beta nicotyrine.
For vaping products, it is recommended to use nicotine of EP grade (European pharmacopeia) in order to limit the presence of alkaloids capable potentially of being harmful to health. The EP grade complies with a standard fixing a limit level of impurities of nicotine among which we find the alkaloids.
Detection method
UHPLC-PDA
Volume required
10ml
Analysis time
10 working days
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The effects of alkaloids on humans are variable according to their typology and their concentration in the product. Certainly, when they are heated using a personnel vaporiser, they can degrade into nitrosamines which are carcinogenic compounds. In particular they are found in tobacco smoke. Harmful for humans, their inhalation has to be controlled and limited.
The ingésciences laboratory offers e-liquid manufacturers and also nicotine producers to analyse its amount by determining the concentration of alkaloids in the product. {0>This service is carried out on the pure nicotine liquid so as to check the total concentration of alkaloids.<}0{>This service is carried out on the pure nicotine liquid so as to check the total concentration of alkaloids.<0} {0>This check forms part of the steps of verification of the conformity with EP grade of a raw material.<}0{>This check forms part of the steps of verification of the compliance with EP grade of a raw material.<0} It is a step necessary for obtaining the e-liquid certification delivered by AFNOR and based on the requirements of standard XP D90-300-2.
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